Vital Wave worked with a global donor that sought to enable dramatic improvements in the performance of HIV priority program use cases through the efficient use of digital applications, tools, and analytics, as well as their effective integration into country programs. In order to meet this goal, Vital Wave led a consultative and data-backed process, including country-level research, that encompassed an actor-level needs assessment, use-case process flow mapping, an inventory of existing relevant tools, applications, and analytics, and an assessment of the ecosystem within which the tools are operated and critical success factors or barriers across variable country contexts. The project resulted in a packaged set of analyses and recommendations to inform future investments to catalyze improvements for country programs.